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Receptor (for messengers) specificity saturation competition antagonist agonist down-regulation up-regulation receptor activation signal transduction pathway transcription factor first messenger second messenger protein kinase tyrosine kinase guanylyl cyclase cyclic GMP (cGMP) cGMP-dependent protein kinase JAK kinase G protein plasma-membrane effector protein adenylyl cyclase cyclic AMP (cAMP) phosphodiesterase cAMP-dependent protein kinase phospholipase C diacylglycerol (DAG) inositol trisphosphate (IP3) protein kinase C calmodulin calmodulin-dependent protein kinase primary response genes (PRGs) Homeostatic Mechanisms and Cellular Communication CHAPTER SEVEN SECTION B KEY TERMS 1.
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